Confusions Over Selection of Potency Will Be Resolved Once You Understand The Concepts Of MIT

“Do not worry much about selection of potencies. Always use 12c-30c, until a better and more accurate way of molecular imprinting is evolved. If your prescription does not act properly or stop acting, and if you are sure you have selected correct similimum, use same drug, same potency from another sample obtained from another source. Collect maximum samples of 30c of same drug from different sources and mix them for better therapeutic result. It would be an eye opening experience, that would compel you to look into the whole ‘potency question’ from a different angle.”

This opening statement may seem a bit controversial an unacceptable to most of homeopaths trained and experienced in classical ways of thinking. Kindly read the whole article and think over it logically before making any hasty conclusions.

A lot of confusions, controversies and phobias exist regarding the selection of potencies to be administered, after selecting the similimum. Everything is controversial in this area of applied homeopathy. Each homeopath has his own ways, and believes that only he is right.Young homeopaths get confused due to totally contradicting advices they get from their different teachers.

Once similimum is selected for a case through a process of exhaustive case taking, repertorization and material medica study, the next issue that bothers a young homeopath the most is the selection of potency, dosage and repetitions.

There are many laws, principles, theories and guidelines, given by different masters, most of them contradicting and conflicting with one another, which makes everything complex for a new comer.

Through hard experience, most homeopaths finally settle into a stage where they make their own ‘private’ ‘laws’ regarding potency, dose and repetition, which they will never expose to the homeopathic community, for fear of being ridiculed as deviation from principles. Everybody wants to appear to be belonging to that respectable class of ‘classical homeopaths’, pretending to be strictly following all the ‘immutable’  ‘cardinal principles’ of ‘pure’ homeopathy.

Please remember, all these ‘laws’ are made and practiced without even knowing what are the active principles of medicines we are using. Everything is pure speculation. Nobody knows what exactly happens during potentization. Nobody knows what are exactly the active principles of potentized drugs. Nobody exactly knows the molecular mechanism by which potentized drugs interacts with biological organism and creates a therapeutic effect. Nobody knows how lo potencies are different from high potencies. Everything is based on speculations. Dynamism, vibrational theory, Vitalism- everything explained as phenomena happening ‘beyond science’.

I am trying to resolve the issue of potencies in the light of scientifically viable working hypothesis regarding homeopathic therapeutics and potentization.

The word ‘drug potency’ and ‘drug potentization’ is associated with the concept of ‘dynamic drug energy’. As per this view, every drug substance has its ‘inherent qualities’, which exist as specific ‘energy’ of dynamic in form, and act up on the ‘vital force’ of organism by a dynamic way. This dynamic drug energy can exist free from ‘material drug, substance and transferred into rectified spirit or sugar of milk through a process called ‘potentization’. By this process, the ‘dynamic drug energy’ gettin freed from the drug substance moves to the potentizing medium and ‘energizes’ it. By the process of serial dilution and succussion, this dynamic energy could be ‘raised’ to new energy levels, and as such, it is believed that ‘higher’ dilutions are more ‘potentized’ and more powerful. This ‘dynamic drug energy’ carried by the ‘potentized drugs’ act upon the vital force and induces a ‘healing process’.

According to the MIT concept I propose, I am explaining the process involved in potentization in terms of ‘molecular imprinting’. It is not the ‘dynamic drug energy’ that is transferred into the medium during so-called process of potentization, but the three dimensional configuration of constituent drug molecules getting imprinted into the supra-molecular matrix of potentizing medium in the form of nanocavities, through a process of forming hydration shells. These nanocavities act as artificial binding sites or artificial ‘key holes’ for pathogenic molecules having configurational similarity to imprinted molecules. This concept scientifically explains the molecular dynamics of homeopathic therapeutics involved in ‘similia similibus curentur’ in a way fitting to the concepts of modern biochemistry, molecular pathology and therapeutics.

Obviously, the term ‘potentization’ reflects the vitalistic philosophy behind it. It would be ideal to use the term ‘molecular imprinting’ to explain the exact process in scientific terms.

Once you understand and accept ‘molecular imprinting’ as the real process involved in potentization, and perceive ‘potentized’ drugs in terms of constituent molecular imprints, all confusions regarding selection of potencies will be scientifically resolved.

According to my concept of ‘molecular imprinting’ involved in homeopathic potentization, the active principles of potentized drugs are ‘molecular imprints’ of constituent drug molecules. Since a drug substance constitutes diverse types of independent molecules in it, potentized drugs also would contain different types of ‘molecular imprints’ or hydrosomes representing those different drug molecules. These ‘molecular imprints’ acts in their individual capacity of configurational similarity by binding up on pathogenic molecules, producing a therapeutic effect.

As per this view, molecules of drug substances would be completely removed from the medium when the dilution crosses Avogadro limit. That means, even the smallest sized drug molecules will disappear above 12c potency. Hence, I proposed that 12c will be the ideal potency for therapeutic purpose, and further higher potencies will not be different from 12c in medicinal property. Since drug molecules will be absent above 12c, I presumed that there is no meaning in continuing potentization higher and higher. On that basis, I suggested to use 12C to 30c potency only. Mean time, we have to work up on developing a better scientific way of producing molecular imprints perfectly

According to me, there only two classes of drugs:

1. Molecular Imprints Forms- potentized drugs above avogadro limit, or 12c and above, containing only molecular imprints or hydrosomes.

2. Molecular Forms- low potencies below 12c and crude drugs which contain original drug molecules.

(Here, the specified probability range is calculated for molecules of lowest molecular weight, using Avogadro Number. Obviously, molecules of higher molecular weight may disappear from the medium at much earlier stages of potentization. Probability range of each individual class of molecules can be calculated using their molecular weight, Avogadro Number and proportions of dilutions).

Drug molecules and their derivatives, due to their gross molecular properties, can chemically interact with biological molecules and metabolites. This phenomenon is utilized when drugs are used as allopathic medicines.

When crude drugs and low potencies are applied as ‘similimum’, the ‘drug’ molecules contained in them, if having configurational similarity to the active groups of pathological molecules, may compete with the pathological molecules in binding to the target bio-molecules, and in that process, relieve the bio-molecules from pathological inhibitions. In this case, drug molecules act as ‘competitive molecular factors’  towards pathologic molecules. It should be understood that crude drugs and low potencies act in certain cases as therapeutic agents by this ‘competitive’ mechanism, when selected according to the principle of ‘similia similibus curentur’.

In certain situations, where there is real scarcity of certain molecules necessary for metabolism, crude substances and low potencies or mother tinctures will have to be used by their supplementary or nutritional value. This belongs to Nutritional Therapy, and should not be confused with homeopathy. Various minerals, vitamins, co-factors, micro-nutrients and amino-acid supplements belong to this category.

Drugs potentized above ‘Avogadro limit’ act by an entirely different molecular mechanism. ‘Hydrosomes’ or ‘molecular imprints’ formed during potentization are configurational complementaries of original drug molecules used as ‘guest’ for potentization. These ‘molecular imprints’ act as ‘counteractive complementary factors’ and bind to the active groups of pathologic molecules having configurational similarity to the drug molecules used for potentization. Thus the pathologic molecules are prevented from interacting with the bio-molecules, thereby relieving the molecular bocks and pathological inhibitions. The danger of drug molecules acting upon on off-target sites, with unfavorable consequences should be expected while using crude drugs and low potencies. If we want to practice real homeopathy, we should deliberately abstain from using medicinal preparations containing drug molecules.

We should also be aware of the difference between crude drugs and low potencies or triturations. Even though both preparations contain same drug molecules, their therapeutic properties are found to be different. In crude form, drug molecules are packed tightly, with their chemical bonds remaining saturated by  interacting with various other molecules or ions. Hence, they are not at all free to exhibit all their individual interactive potentials. Whereas in triturations and low potencies, the drug molecules are free or ionized, they can exhibit all their properties. Hence, pathogenic and therapeutic capabilities of triturations and low potencies are much higher to crude forms of same drug, whereas drugs of toxic nature are more toxic in crude forms than dilutions, due to their high concentration of molecules. We already know that various drugs which appear  comparatively inert in their crude forms become very potent medicinal agents in triturated forms. Differences between crude Siliciea and Silice 3x, crude Lyco and Lyco 3x etc. are examples for this phenomenon.

But many homeopaths, even those who were not reluctant to accept my ‘molecular imprint’ concept, invited my attention to their experience that when a drug in 12C- 30c potency acted for some time, a stage reaches where no further improvement is obtained. In such situations, they could create curative response by going to higher and higher potencies of same drug. My friends said that their experiences does not corroborate my suggestion that a drug in all potencies above 12c will be similar in medicinal properties.

I decided to take up this question seriously, and started working up on it. There were many instance where NUX 30 failed but NUX 200 acted. It was also correct that in some cases NUX 30 acted for some time and then came to a standstill, where repeating same potency did not succeed in evoking any response. Then NUX 30 or NUX 1m acted favorably.

There were another experience reported by some homeopaths, and verified by me. When NUX 1m failed, NUX 30 or NUX 200 acted. In my experiments on that lines, I noticed that when a case comes to standstill after a certain period of improvement after using NUX 1m, administration of NUX 30 or NUX 200 was also beneficial, instead of moving to still higher potencies.

Then I started experimenting on another lines. When NUX 30 failed to provide further improvement after a certain stage, I used NUX 30 from another sample obtained from another manufacturer. The result was wonderful. It acted!. I repeated this experiment with different cases, different drugs,  different potencies. Finally I came to the conclusion that it was not a question of going higher or lower, but changing of samples, changing of source of potentized drugs. I can now suggest my friends, if you fail with NUX 30, and your are still convinced that the similimum is NUX, use NUX 30 obtained from another manufacturer. It will work. Always keep maximum samples of same drugs in same potencies obtained from different sources, and try all of them before changing your prescription. I have also seen it beneficial to mix all those different samples together and keep as single drug. For example, you can collect NUX 30 from five different manufacturers and mix them together and keep labeled as NUX. And see the difference!

It is not at all realistic to imagine that the same drug sample of Nux Vomica used for proving is always used for preparing its potencies also. It may have been procured and prepared from another location, climate, environment, time and circumstances. All of these factors may necessarily influence their chemical constitution also. Contaminants and pollutants also differ with time, place and persons who handled it. Yet, we are obliged to call all these different samples as Nux Vomica, and use it as same drug.

In reality, samples of potentized Nux Vomica we get now from pharmacies are prepared from samples very much different from the samples used for proving it two hundred years back. It might not necessarily be the same contaminations and foreign molecules which happen to be mixed with the drug during procurement and potentization. Entirely new type of impurities and foreign molecules, different from proven samples, shall definitely get mixed with drugs while potentizing. Naturally, these contaminants and foreign molecules also get subjected to potentization along with original drug molecules. It is evident that the homeopathic potencies of Nux Vomica we get from pharmacies contain the potentized forms of these new contaminant molecules also. In other words, they are mixed with potentized forms of these unknown substances, entirely different from those were subjected to proving. We cannot ignore the fact that we are not using potencies of same drug, that have been proved earlier and recorded in the materia medica, eventhough we call it with same name. It is composed of an entirely different mixture, much more different in molecular structure from the one subjected to original proving. We use the potentized form of this new combination, on the basis of symptoms produced by another combination earlier, using the therapeutic principle ‘Similia Similibus Curentur’. Is not this realization somewhat emberassing? We have to provide convincing solutions to the ethical, theoretical and practical problems raised by this situation.

Logical explanation for this phenomenon is very simple. It is associated with the process of molecular imprinting happening in potentization, and the quality of crude drug sample used for potentization. Simply put, each sample of same drug in same potency may differ in their constituent molecular imprints. One sample may miss some ‘molecular imprints’ that may be present in another sample. Each sample provides only partial curative effect, according to the availability of ‘molecular imprints’ present in them. To get a ‘complete’ therapeutic action of a particular drug, we have to use different samples from different sources, one after other, or mixing together.

Then regarding so-called ‘ultra-high’ dilutions. If the process of dilution is done strictly as per directions given by Samuel Hahnemann, 99 ml alcohol/water mixture has to be thrown away to get 1 ml of 1c potency, which is used as the back potency for 2c stage of potentization. That means, to prepare 1ml of DM potency we will have to throw away 999999.999 litres of water/ alcohol mixture. Do you believe one lac litres of ethyl alcohol is thrown away by the manufactures while preparing 1 ml of homeopathic medicine in DM potency? If you claim that this is not thrown away but kept as various potencies, can you imagine the size of storage facilities required for each drug? Please remember, we have around 1000 drugs in homeopathy, which means 1000000000 litres of wastage of ethyl alcohol-water mixture! And also calculate the time, energy utensils, bottles and labor required for handling all this! Do you believe all this happening?

Every manufacturer claim that they use back potencies, and hence no wastage of alcohol happens. But somebody in the line has to do the job of raising 30c into 199c, 200c into 999c, 1m into 9999c and so on. If those people do it genuinely as per Hahnemannian method, they will have to bear all these wastage, and the cost of back potencies will be unimaginably high!

In the present atmosphere of profit-oriented pharmaceutical business managed by professional business administrators, we cannot be so naïve to believe that the manufacturers of homeopathic medicines would be so much dedicated to the philosophy of Hahnemann to bear such huge holes in their money bags. Remember, these same people are flooding the market with all sorts of unethical patented mixtures in the name of homeopathy, and bribing the homeopaths to market them, in their greed to amass wealth. How can we expect them to be so much sincere in the service of homeopathy only while preparing potencies? How much pathetic is the situation since there exist no any scientific mechanism to verify the exact identity and potency of a drug other than to trust the labels on the bottles! If somebody make an error knowingly or unknowingly in sticking a label to a stock bottle of back potency, can you imagine the consequences that will continue to haunt generations of homeopaths to come? We have to be consoled that potentized homeo medicines cannot kill human beings.

Believe it or not,if you closely monitor what is happening behind the walls of commercial homeopathic manufacturing units, you will lose all your trust in our ‘very high’ potencies. I had personally discussed with some retired supervisors and managers of certain famous production units, and they confessed some bitter truth.  After 30c, most units do not carry on potentization strictly as Hahnemann directed. A few additional shakes is given to 30c and marked as 199c, which is used as the back potency for 200c. Again with few additional shakes, and 200c becomes 999c used as back potency  for 1m. Over all, we can see that practically, in most cases, the difference between 30c and DM potency is only a four to ten stage dilution and a few additional shakes!. Finished! And we call it ‘ultra-high’ potencies!. Only consolation is that 30c is enough for optimum molecular imprinting to happen, and our drugs will work if used as similimum, since they contain ‘molecular imprints’, and that is enough. This shows that the difference between 30c and CM or DM is very narrow. Our talk about ‘very high’ dilution is practically meaningless. Most homeopaths and manufacturers will not tolerate my statement, because that may undermine the ‘sand hills’ of fame they have built in the name of ‘high potencies’.

Most homeopaths believe that administration of incorrect remedies and potencies may harm the patients. If that were the case, homeopaths would have been the greatest criminals in human history! They would have already harmed the whole human race by the time being through wrong prescriptions. Even you and me make many many wrong prescriptions everyday, believing that we are making correct prescriptions. Can anybody deny it with a sincere heart?



What is the optimum potency, as per MIT? Now I would say ‘ALPHA MOLECULAR IMPRINTS’- I have explained this idea in a separate article



  1. thanks for this and it is really avery good and informative article.In my view the potency matter should be clearly in our text books for young students.

  2. Chandran Nambiar

    It would be a good decision, indeed. If we selected right drug for the ‘patient’, it will cure in 30c, beyond any doubt. If the action seems to stop after a while, and indications are same, get same drug same potency from a different source and apply.

  3. thank u sir for giving good knowledge regarding selection of potency of homeopathic medicines
    from today i only use 30c potency

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